Introduction: The success of the prosthetic rehabilitation is a factor of the periodontal reactions. Hence, in the current study, we aim to assess bone loss in the osseointegrated implants posttreatment by the cone beam computed tomography (CBCT) imaging. Materials and Methods: We conducted a prospective clinical observational study among 50 subjects who received mandibular dental implants for the replacement of the single lost anterior tooth. The follow-up was done at 1 week, 2 weeks, and after 6 weeks. The bone loss around the implant was noted by imaging with CBCT. The values were compared and analyzed statistically. Results: We observed a significant variation among the genders and the age groups. The mean bone loss around the implants was statistically significant for the different time intervals (P = 0.001). Conclusion: Significant bone loss was noted in the first few weeks after implantation. Care should be focused in the initial posttreatment phase to eliminate the factors aggravating the periodontitis.