Four cases of Mycetoma especially among farmers were confirmed both by demonstrating granules in histopathological sections and by isolating Madurellagrisea in two patients, Madurellamycetomatis in one and Nocardia asteroids in one, following retrieval trauma. Eumycotic and Actinomycotic agents produce severe morbidity. One cases of Actinomycoticmycetoma responded to Trimethoprim-Sulphamethasone and the remaining three had antifungal Ketaconazole therapy for six months and did not return up for further follow up. These four cases are being reported here for its unusual clinical manifestations of multiple blisters in the extremities without the sinus tract formation and clinically mycetoma could not be diagnosed and indicates the need for biopsy examination and mycology culture.