Report Leukemia cutis as an initial presentation in a case of mixed phenotype acute leukemia: a double jeopardy

Stephen, Norton and Jeyaraman, Rajashree and Srinivas, Bheemanathi Hanuman and Dileep, Jude and Nagendran, Prabhakaran and Manivannan, Prabhu (2024) Report Leukemia cutis as an initial presentation in a case of mixed phenotype acute leukemia: a double jeopardy. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 17.0 (8). pp. 252-256. ISSN 1936-2625

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Open Access PDF Link: https://doi.org/10.62347/acdg7634

Abstract

Leukemia cutis (LC) is defined as infiltration of the skin by leukemic cells resulting in clinically recognizable cutaneous lesions. The lesions range from violaceous papules, plaques, nodules, blisters, maculopapular rash and as erythroderma. LC can precede or happen after the presentation of leukemia. Here, we report a case of Mixed phenotype Acute leukemia (MPAL) presenting as LC (erythematous & violaceous nodules) which is a rare as well as a grave combination as it carries a worse prognosis. Here, we present a case of MPAL which presented as Leukemia Cutis proven on biopsy. The paper discusses the importance of identifying LC both in a clinical and a pathological pretext as it is important to start the Chemotherapy for MPAL at the earliest for a better outcome.

Item Type: Article
Uncontrolled Keywords: Leukemia cutis, mixed phenotype acute leukemia, nodules
Subjects: Medicine > Oncology
Medicine > Pathology
Divisions: Engineering and Technology > Aarupadai Veedu Institute of Technology, Chennai, India
Medicine > Aarupadai Veedu Medical College and Hospital, Puducherry, India
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 06 Feb 2026 07:12
URI: https://ir.vmrfdu.edu.in/id/eprint/6950

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