Sekar, Priyanka and Dominic, Melvin and Balakrishnan, Sudhiersharan and Sreelakshmi, V. K. and Haneendhar, R. and Gopan, S. Jithin and Rathnasami, Pragnesh and Moturi, Sai Vineeth (2025) Post-COVID-19 Complications: A Study on Long COVID Symptoms and Their Pathophysiology. JOURNAL OF PHARMACY AND BIOALLIED SCIENCES, 17.0 (SUPPL ). S2557-S2559. ISSN 0976-4879
Full text not available from this repository.Abstract
Background:Long COVID refers to persistent symptoms lasting weeks or months after recovery from acute COVID-19. These symptoms can affect multiple systems and impair quality of life.Objective:To assess the prevalence, pattern, and probable pathophysiological mechanisms of long COVID symptoms in recovered patients.Materials and Methods:A cross-sectional study was conducted over 12 months among 210 adults recovered from COVID-19 (>= 12 weeks postinfection). Clinical evaluation, lab investigations, and imaging were used to identify post-COVID symptoms and explore underlying mechanisms.Results:Common symptoms included fatigue (67.6%), breathlessness (42.8%), cognitive issues (39.5%), and myalgia (34.7%). Neuropsychiatric complaints were noted in 41%, while 29% had cardiopulmonary sequelae. Elevated inflammatory markers correlated with symptom persistence (P < 0.05).Conclusion:Long COVID involves diverse symptoms, primarily fatigue and neurorespiratory complaints. Immune dysregulation and systemic inflammation appear central to its pathophysiology.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Breathlessness, fatigue, inflammation, long COVID, post-viral syndrome |
| Subjects: | Pharmacology, Toxicology and Pharmaceutics > Pharmacology & Pharmacy |
| Divisions: | Medicine > Vinayaka Mission's Kirupananda Variyar Medical College and Hospital, Salem > Emergency Medicine Medicine > Vinayaka Mission's Kirupananda Variyar Medical College and Hospital, Salem > General Medicine |
| Depositing User: | Unnamed user with email techsupport@mosys.org |
| Last Modified: | 06 Feb 2026 07:11 |
| URI: | https://ir.vmrfdu.edu.in/id/eprint/6817 |
Dimensions
Dimensions