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DimensionsSagar, K. V. S. B. Vidya and Jyotsna, P. Sarat and Sethumadhavan, K. and Bandaru, Narasinga Rao (2024) Cytokine levels in Type-2 Diabetes Mellitus (T2DM) Patients with Asymptomatic Bacteriuria (ASB) in Northern Andhra Pradesh. JOURNAL OF PURE AND APPLIED MICROBIOLOGY, 18.0 (2). pp. 1246-1252. ISSN 0973-7510
Full text not available from this repository.Abstract
Diabetes is a systemic inflammatory condition. The modulation of cytokine levels caused by Asymptomatic Bacteriuria (ASB) infection can lead to altered inflammatory status in various tissues and may affect their homeostasis and function. We aim to estimate the cytokine (IL-6, TNF-alpha and IL-10) levels in serum of diabetic individuals with and without ASB to study their clinical significance. The current study evaluates the role of cytokines in inflammation caused due to ASB in T2DM patients. Increase in IL-6 and TNF-alpha levels may indicate renal tissue damage caused due to inflammation by ASB. Whereas increased IL-10 levels is a possible indicator of persistent infection with bacteria which may lead to diabetic renal disease.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | Diabetes Mellitus, Asymptomatic Bacteriuria, Cytokines, Inflammation |
| Subjects: | Biochemistry, Genetics and Molecular Biology > Biotechnology & Applied Microbiology Immunology and Microbiology > Microbiology |
| Divisions: | Medicine > Aarupadai Veedu Medical College and Hospital, Puducherry, India > Microbiology |
| Depositing User: | Unnamed user with email techsupport@mosys.org |
| Last Modified: | 06 Feb 2026 06:59 |
| URI: | https://ir.vmrfdu.edu.in/id/eprint/6540 |
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