Influence of BIS monitoring, obesity severity and anesthetic agents on recovery outcomes in obese patients undergoing laparoscopic surgery: A multivariate analysis

Gnanasigamani, John Peter and Balasubramanian, Arunkumar and Rathnasabapathy, Brindha and Pandian, Naveena and Periasamy, Panneerselvam and Choudhary, Arbind Kumar (2025) Influence of BIS monitoring, obesity severity and anesthetic agents on recovery outcomes in obese patients undergoing laparoscopic surgery: A multivariate analysis. ANAESTHESIA PAIN & INTENSIVE CARE, 29.0 (3). pp. 665-673. ISSN 1607-8322

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Abstract

Background & objective: Bispectral Index (BIS) monitoring is widely used to optimize anesthetic depth, but its impact on perioperative recovery outcomes in obese patients undergoing laparoscopic surgery remains unclear. This study evaluates the role of BIS monitoring in postoperative recovery, anesthetic consumption, and hemodynamic stability in this population. Specifically, this study aimed to determine whether BIS monitoring reduces anesthetic consumption, shortens recovery times, improves hemodynamic stability, and enhances patient satisfaction compared to standard anesthesia management. Methodology: This prospective, randomized controlled trial included 130 obese patients (BMI >= 30 kg/m2) undergoing laparoscopic cholecystectomy, hernia repair, or sleeve gastrectomy. The patients were randomized into BIS-monitored (n = 64) and Non-BIS (n = 66) groups. Anesthesia was maintained using sevoflurane or desflurane, with BIS titrated to 40-60 in the BIS group. Primary outcomes included time to emergence, time to extubation, and the Post-anesthesia Care Unit (PACU) stay. Secondary outcomes assessed anesthetic consumption, hemodynamic stability, postoperative complications, and patient satisfaction. Results: BIS monitoring significantly reduced time to extubation (11.56 +/- 4.29 vs. 12.80 +/- 4.40 min, p = 0.025) and PACU stay (59.00 +/- 17.65 vs. 60.95 +/- 17.32 min, P = 0.041). No significant differences were observed in MAP, HR, or anesthetic consumption (P > 0.05). Postoperative complications were comparable between groups, but patient satisfaction scores were slightly higher in the BIS group (8.35 +/- 1.60 vs. 7.90 +/- 1.88, P = 0.078). Conclusion: BIS monitoring significantly improves postoperative recovery by reducing extubation time and PACU stay, but does not significantly alter intraoperative hemodynamic stability or anesthetic consumption. These findings suggest that BIS monitoring may enhance postoperative recovery in obese patients undergoing laparoscopic surgery. Further research is needed to assess its impact in more complex surgical settings.

Item Type: Article
Uncontrolled Keywords: BIS monitoring, Obesity, Laparoscopic Surgery, Postoperative Recovery, Anesthetic Consumption, Hemodynamic Stability
Subjects: Medicine > Anesthesiology
Divisions: Medicine > Vinayaka Mission's Medical College and Hospital, Karaikal > Anaesthesiology
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 06 Feb 2026 06:59
URI: https://ir.vmrfdu.edu.in/id/eprint/6428

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