BACKGROUND Psoriasis is one of the most common skin condition in dermatology. The association of metabolic syndrome is increasing in psoriatic patients. To educate and treat the patients for the associated conditions is equally important. Aim is to estimate and co-relate the association of obesity, lipid profiles, blood pressure and blood sugars (metabolic syndrome), and evaluate the cardiovascular risk in psoriatic patients. MATERIALS AND METHODS A clinical study of 50 conformed cases of psoriasis who attended the outpatient department of dermatology were studied. ECG, lipid profiles and relevant investigations were done. At the same time, 20 healthy individuals (controls) were also studied. Leven's test for equality of variances and t-test for equality of means are used. P value of < 0.05 was significant. RESULTS Out of Hypertension, Diabetes, Obesity and Hyperlipidaemia any two were positive in one case (2.79%), any three were positive in 14 cases (38.88%), and all four were positive in 21 cases (58.33%). Among control, 1 was suffering from metabolic syndrome. When compared to control, the P value was significant for body mass index (BMI), blood sugars, hypertension. CONCLUSION Psoriasis is a definite risk for metabolic syndrome and cardiovascular morbidity. So early diagnosis and treatment for metabolic syndrome is equally important along with treatment of psoriasis.