Chronic Renal Failure is a worldwide public health problem with an increasing incidence and prevalence, poor outcomes and high costs. The health teaching regarding hemodialysis and self care is important to improve the health and well being for patients with chronic renal failure. The aim of the study was to evaluate the effectiveness of video assisted teaching on knowledge and attitude regarding hemodialysis among patients with chronic renal failure. Pre experimental one group pretest post design was used. The setting of the study were out patient department at Dhanalakshmi Srinivasan Medical College and Hospital.50 samples were selected by non probability purposive sampling technique. After self introduction and explanation, the participants were given questionnaire to fill. The post test was done after the video assisted teaching, two weeks later. Result of the study were mean post test score of knowledge level 22.72 (SD +/- 3.81)was significantly higher than the mean pre test score 14.31 (sd-3.67) and the mean difference were 8.38. Paired`t' value 28.28 (table value =2.02) which is significant ant p <0.05 level, for attitude, the mean post test score 74.66 (SD +/- 7.31) was significantly higher than the mean pre test score 65.82 (sd-6.92) and the mean difference was 8.84. Paired t value of knowledge and attitude, the finding revealed that the mean value of knowledge is 22.72 with SD (3.81) and the mean value of attitude is 74.66 with SD (7.31) project `r' value of 0.329 (table value=0.273) which shows positively mild correlation. The result reveals that there is a significant association between the knowledge and the demographic variables of food habits, educational qualification and duration of dialysis and significant association between the attitude and the demographic variables of age and educational qualification (table value =3.84, p <0.05). The finding revealed that there is a significant improvement in knowledge and attitude after intervention.