Nanotechnology has started to become an extraordinary value in the field of dental sciences. At the same time, continual refinement of traditional methods, developments of improved materials and advanced medications, and pharmacological approaches have enhanced dental care methodology and technique. The physical-chemical properties attained by dental materials with nanometric particles reinforced have augmented the efficiency of dental materials. This article gives an introspective review of the applications of molecular engineering techniques to the dental sciences, and how these new techniques are contributing to the development of new dental materials and improve the existing materials. These new techniques of reinforcing nanosilver in acrylic resin offer an array of possibilities of bearing enormous impact in the physical and biological property of the denture base material. Development of such novel materials can be directly applied in the dental profession.