Over the last few decades, there has been a significant awareness established to accept the idea of biotechnology in the field of construction. This growth in awareness has occurred tremendously. In today’s world, the development of new building materials and processes that make use of biobased components, such as microorganisms and materials that are mediated by microbes, is an example of developing scientific technology. In general, building materials that are produced through the use of biotechnology, such as cement and grout, are seen as being environmentally benign, affordable, and sustainable. In contrast to traditional cementitious materials, bio-based cementitious materials has the potential to considerably contribute to a large role in reducing the negative impact that the building sector has on the surrounding environment. The purpose of this review work is to present a contemporary evaluation of biotechnology and biobased materials to assess existing developments and suggest new prospective routes for the advancement of construction biotechnology. Based on this study, it was observed that the inclusion of biotechnology can significantly increase the engineering behaviour of cement concrete and weak foundation soil. Hence, its was recommened to implement the idea of biotechnology as effectively in the building industry to obtain the major environmental and economic benefits it offers. © 2024 Elsevier B.V., All rights reserved.