Dear Editor, From a scientific perspective, snail mucus, or snail secretion filtrate (SSF), has emerged as a significant discovery in dermatology and regenerative medicine. Several studies on mucus composition have illuminated its features in recent years, yet much remains unexplored. High-quality snail mucus contains adequate levels of active substances (e.g., allantoin, glycolic acid, proteins, glycosaminoglycans, and polyphenols). It comprises a complex mixture of proteins, enzymes, peptides, and trace minerals produced both externally and internally, which improves skin hydration, flexibility, and smoothness. This makes it an ideal ingredient for anti-aging creams, moisturizers, and serums. The beauty and pharmaceutical industries popularize commercial SSF products due to their natural composition and scientifically proven performance as a promising dermatological treatment. These products offer synergistic therapeutic effects, including cell signaling, tissue growth, tissue repair, wound healing, hydration, anti-aging properties, and exfoliation. Read more in the PDF. This record is sourced from MEDLINE/PubMed, a database of the U.S. National Library of Medicine