All the designed medicines are used to cure or treat the disease, otherwise, to prevent the disease. In last few years the field of pharmacovigilance has evolved significantly. Mining the data or knowledge discovery from the huge amount of data, several algorithms are developed. The application of data mining in the field of pharmacovigilance will give the predictable result in the field of analysis. The making of safety database available in the global, will improve communication for the safety issues on a frequent manner. This paper discusses techniquesof usefulness of data mining techniques in the field of pharmacovigilance, future trends and role of the data mining in pharmacovigilance. © 2017 Elsevier B.V., All rights reserved.