Cytotoxic effects of the nickel release from the stainless steel brackets: An in vitro study

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Pillai, AjithRajasekharan and Gangadharan, Anil and Gangadharan, Jithin and Kumar, NallasamyVijaya (2013) Cytotoxic effects of the nickel release from the stainless steel brackets: An in vitro study. Journal of Pharmacy And Bioallied Sciences, 5 (5). p. 1. ISSN 0975-7406

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Abstract

Aims: To determine if nickel released from stainless steel brackets has cytotoxic effects on gingival fibroblasts. Materials and Methods: Brackets, an essential part of fixed orthodontics, were tested for cytotoxic activity using MTT and comet assays. Results: Nickel leached from brackets can damage fibroblasts. Conclusion: Minimal nickel concentration of 1.18 μg can damage human gingival fibroblasts. Different bracket brands release non-uniform nickel levels. © 2014 Elsevier B.V., All rights reserved.

Item Type: Article
Subjects: Biochemistry, Genetics and Molecular Biology > Biochemistry
Biochemistry, Genetics and Molecular Biology > Genetics
Biochemistry, Genetics and Molecular Biology > Molecular Biology
Chemical Engineering > Bioengineering
Pharmacology, Toxicology and Pharmaceutics > Pharmacology
Pharmacology, Toxicology and Pharmaceutics > Pharmaceutics
Pharmacology, Toxicology and Pharmaceutics > Toxicology
Divisions: Dentistry > Vinayaka Mission‘s Sankarachariyar Dental College, Salem > Oral and Maxillofacial Surgery
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 10 Dec 2025 06:54
URI: https://ir.vmrfdu.edu.in/id/eprint/4239

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