Osteosarcoma (OS) is a commonly encountered bone malignancy. It is an aggressive lesion which usually follows a fatal course. Osteosarcoma of jaw bones are rare, representing only 4 to 8% of all osteosarcomas which makes this case interesting to report. A case of OS affecting the mandible of a 35-year-old male which is rare is presented here along with literature review. © 2015 Elsevier B.V., All rights reserved.