A case–control study to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus

Vijayalakshmi, Lakshmanan and Raj, JosephBabhu Susai and Kavitha, Jayavel and Krishnaraj, Selvaraj and Manovijay, Balagangadharan and Manikandan, Dhanasekaran (2020) A case–control study to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus. Journal of Pharmacy And Bioallied Sciences, 12 (5). p. 389. ISSN 0975-7406

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Abstract

Aim: The aim of this study was to evaluate candidal parameters in the oral cavity of patients with type 2 diabetes mellitus (DM). Materials and Methods: The samples included in the study were divided into two groups: group A, comprises 50 patients with type 2 DM, and group B, comprises 30 subjects who were nondiabetic. A nonrandom consecutive sampling technique was used to enroll the subjects for the study. The χ2 test was used to examine the characteristics of the samples. Results: The results found that there is a significant difference in saliva and swab for Candida growth between patients with type 2 DM and normal healthy individuals. Swab had shown slightly more Candida growth than saliva in group A (type 2 DM). No significant variation in Candida growth was found. Candida krusei was seen in normal healthy individuals alone. In antifungal susceptibility pattern to various antifungal agents, Candida tropicalis has shown a significant result for various antifungal agents whereas Candida albicans and Candida dubliniensis did not show any significant result for various antifungal agents used in group A (patients with type 2 DM). Conclusion: Diabetic individuals who are prone to a hyperglycemic state favors the growth and establishment of Candida species. Although a smaller percentage of multidrug-resistant Candida species has been observed in the saliva of patients with type 2 DM. © 2020 Elsevier B.V., All rights reserved.

Item Type: Article
Subjects: Pharmacology, Toxicology and Pharmaceutics > Pharmacology & Pharmacy
Biochemistry, Genetics and Molecular Biology > Genetics
Biochemistry, Genetics and Molecular Biology > Molecular Biology
Chemical Engineering > Bioengineering
Pharmacology, Toxicology and Pharmaceutics > Pharmacology
Pharmacology, Toxicology and Pharmaceutics > Pharmaceutics
Pharmacology, Toxicology and Pharmaceutics > Toxicology
Divisions: Nursing > Vinayaka Mission's Annapoorna College of Nursing, Salem
Medicine > Vinayaka Mission's Medical College and Hospital, Karaikal
Nursing > Vinayaka Mission's College of Nursing, Karaikal
Nursing > Vinayaka Mission's College of Nursing, Puducherry
Pharmacy > Vinayaka Mission’s College of Pharmacy, Salem
Physiotherapy > Vinayaka Mission's College of Physiotherapy, Salem
Homoeopathy > Vinayaka Mission's Homoeopathic Medical College and Hospital, Salem
Medicine > Vinayaka Mission's Kirupananda Variyar Medical College and Hospital, Salem
Arts and Science > Vinayaka Mission's Kirupananda Variyar Arts and Science College, Salem, India
Engineering and Technology > Vinayaka Mission's Kirupananda Variyar Engineering College, Salem, India
Law > Vinayaka Mission's Law School, Chennai
Medicine > Vinayaka Mission's Medical College, Kottucherry
Medicine > Vinayaka Mission's Medical College, Puducherry
Physical Education > Vinayaka Mission's College of Physical Education, Salem
Interdisciplinary Studies > Vinayaka Mission's School of Health Systems, Chennai
Dentistry > Vinayaka Mission‘s Sankarachariyar Dental College, Salem
Liberal Arts > Vinayaka Mission's School of Economics and Public Policy, Chennai
Depositing User: Unnamed user with email techsupport@mosys.org
Last Modified: 04 Dec 2025 11:45
URI: https://ir.vmrfdu.edu.in/id/eprint/3432

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