The integration of cutting-edge technology, such as cloud computing and Clinical Decision Support (CDS) algorithms, is radically altering the healthcare system. This research digs into how Inference Engines, Bayesian Networks, Machine Learning Algorithms, and Natural Language Processing (NLP) have all played critical roles in reshaping the healthcare industry. Medical professionals may more efficiently use CDS algorithms thanks to cloud-based technologies that streamline data storage, sharing, and processing. Decision-making is aided by Inference Engines because they provide organized insights based on preset criteria. This is where Bayesian Networks come in, with their ability to represent complicated, probabilistic interactions among variables for exact diagnoses and risk assessment. Machine learning algorithms improve predictive analysis by identifying trends in large datasets, paving the way for more individualized approaches to medical care. Chatbots and sentiment analysis are only two examples of how NLP is transforming the doctor-patient relationship by teaching computers to understand human language. Those in the medical field may greatly increase their diagnostic precision, treatment efficiency, and patient outcomes by adopting these innovations. © 2024 Elsevier B.V., All rights reserved.