A prospective study to compare the effect of lignocaine with adrenaline injection versus plain lignocaine injection as an effective peribulbar block for anaesthesia in ocular surgery for patients with hypertension

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Ramalingam, Kothai and Krishnamoorthy, Kathiravan and Padmanaban, Lavanya and Angamuthu, Naresh and Balasubramanian, Arul and Choudhary, R. Arbind Kumar (2025) A prospective study to compare the effect of lignocaine with adrenaline injection versus plain lignocaine injection as an effective peribulbar block for anaesthesia in ocular surgery for patients with hypertension. Health Biotechnology and Biopharma, 9 (1). 48 - 67. ISSN 25384414

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Abstract

This randomized trial compared plain lignocaine versus lignocaine with adrenaline for peribulbar anaesthesia in hypertensive patients undergoing ocular surgery. One hundred hypertensive patients were assessed for anaesthesia onset time, pain levels, blood pressure, pulse rate, and intraocular pressure. The lignocaine-adrenaline group demonstrated faster onset (3.2 ± 0.5 vs 5.1 ± 0.7 min) and reduced pain, with similar hemodynamic stability in both groups. © 2025 Elsevier B.V., All rights reserved.

Item Type: Article
Additional Information: Cited by: 0
Uncontrolled Keywords: epinephrine; lidocaine; adult; age distribution; anesthesia; Article; cataract extraction; clinical practice; comparative effectiveness; controlled study; demographics; diastolic blood pressure; drug effect; eye surgery; female; hemodynamics; human; hypertension; hypertensive patient; intraocular pressure; major clinical study; male; observational study; pain intensity; peribulbar anesthesia; phacoemulsification; prospective study; pterygium; pulse rate; pupil diameter; randomized controlled trial; sex ratio; systolic blood pressure; visual analog scale
Subjects: Biochemistry, Genetics and Molecular Biology > Biotechnology
Medicine > Pharmacology (medical)
Pharmacology, Toxicology and Pharmaceutics > Pharmacology
Pharmacology, Toxicology and Pharmaceutics > Pharmaceutics
Pharmacology, Toxicology and Pharmaceutics > Toxicology
Divisions: Pharmacy > Vinayaka Mission’s College of Pharmacy, Salem > Pharmacy
Pharmacy > Vinayaka Mission’s College of Pharmacy, Salem > Pharmacology
Pharmacy > Vinayaka Mission’s College of Pharmacy, Salem > Pharmacy Practice
Depositing User: Unnamed user with email techsupport@mosys.org
Date Deposited: 25 Nov 2025 06:10
Last Modified: 25 Nov 2025 06:10
URI: https://ir.vmrfdu.edu.in/id/eprint/157

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